Metrohm - Analytical solutions for the pharmaceutical industry

Metrohm AG, headquartered in Switzerland, is a leading provider of solutions for analytical chemistry. Founded in 1943, Metrohm is present in more than 80 countries around the globe with subsidiaries and exclusive distributors. Metrohm provides its customers with high-precision analytical instrumentation, application expertise and comprehensive services. Metrohm's product range offers ideal solutions for the pharmaceutical market; e.g. for active pharmaceutical ingredient (API) and impurity analysis as well as process monitoring and quality control applications.

Vis-NIR and Raman spectroscopy: improving QC along the production chain

Spectroscopy enables rapid and non-destructive analysis of raw materials as well as intermediate and finished products. Metrohm's portfolio includes combined visual and near-infrared laboratory analysers with a dedicated pharma software version, process spectrometers for PAT procedures in accordance with FDA regulations and handheld Raman spectrometers for quick materials identification and verification.

Incoming materials inspection

Mira M-3 handheld Raman spectrometers are the instruments of choice for incoming materials inspection. These smartphone-sized instruments allow users to verify incoming materials in 15 to 20 seconds on average, with a simple "Pass" or "Fail" result. The instrument's software complies with FDA 21 CFR Part 11 regulations.

Real-time quality monitoring of the production process

Inline process monitoring can be implemented with near-infrared spectroscopy process analysers from Metrohm Process Analytics in compliance with FDA PAT procedures. Process technologies such as these allow manufacturers to monitor their processes in real time.

Finished-product QC: fast and non-destructive

NIR spectrometers from Metrohm are capable of analysing finished products; e.g., creams, gels, solutions, tablets or capsules, without tedious sample preparation or the use of reagents. The analysis is direct, non-destructive and faster than reference methods (e.g., HPLC).

Wet-chemical methods: potentiometric and Karl Fischer titration

Metrohm offers a wide range of instrumentation for potentiometric titration as well as water content determination with volumetric and coulometric Karl Fischer titration. Metrohm's titration portfolio covers everything from simple stand-alone titrators to integrated systems for automated determination and software for full regulatory compliance (e.g., FDA 21 CFR Part 11).

Ion chromatography for all requirements

In the field of ion chromatography, Metrohm offers excellent value for money. Metrohm's ion chromatography systems and sample preparation solutions are robust and reduce the need for consumables. In addition, Metrohm offers a ten-year warranty on the anion suppressor and a full range of separation columns, detectors and automation options.

Process analysers for online monitoring in any environment

From single-parameter and single-method analysers to versatile multiparameter analysers, Metrohm Process Analytics develops instruments for near real-time monitoring in manufacturing processes.

pH meters, stability analysers, voltammetry/CVS, electrochemistry

Instruments for pH, conductivity and oxidation stability measurement as well as a wide range for voltammetry/cyclic voltammetric stripping and electrochemical research round off the Metrohm product portfolio.

Committed to service excellence and application expertise

Metrohm is strongly committed to providing the best support and service possible - from consulting, installing (IQ/OQ service), training and preventive maintenance to application support. Moreover, Metrohm provides on its website free access to a multitude of pharma applications compliant with USP and Ph. Eur.

Products and Services

Contact Details

Metrohm AG
Ionenstrasse
CH-9100 Herisau
Switzerland
Tel: +41 71 353 85 85
Fax: +41 71 353 89 01
URL: www.metrohm.com

Metrohm is a leading provider in equipment for analytical chemistry.
Vis-NIR and Raman spectroscopy for rapid, non-destructive analysis along the entire production chain, from incoming materials inspection to finished product QC.
Instant materials verification of raw materials with a Mira M-3 Raman spectrometer. The instrument can analyse through bags, bottles and vials.
NIRS Process Analysers for inline, real-time process monitoring compliant with the FDA’s PAT initiative.
Committed to service and application excellence: Metrohm provides unsurpassed service for instrument installation, maintenance and training.
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