Evonik - Coat tales

Evonik is one of the world leaders in the manufacture and supply of functional excipients for the pharmaceutical industry, with more than 50 years of formulation experience with EUDRAGIT. The company offers a wide range of polymethacrylate excipients that can be considered a versatile and flexible toolbox: you can achieve the desired drug-release profile by using one EUDRAGIT polymer alone or a combination of various polymers.

Different chemical groups make the polymers acid- or base-soluble or permeable, thus controlling the optimal release of the active ingredient.

There are many challenges in the pharmaceuticals sector today, not the least of which is improving production efficiency. With the new coating system additive PlasACRYL T20, Evonik now supports its customers by offering a unique and simple way to optimise coating formulations, reduce processing times and achieve significant cost savings in their operations. This is a ready-to-use product applied as a substitute for conventional GMS systems and talc. It is a 20% aqueous dispersion that contains the anti-tacking agent glycerol monostearate (GMS, mono- and diglycerides NF), the plasticiser triethyl citrate and the emulsifier polysorbate 80. All the raw materials in this coating system are of pharmacopoeial quality.

One additive, numerous benefits In terms of production costs and processing time, this type of coating allows Evonik's customers to achieve better results than with their regular GMS or talc systems. Faster preparation times are achieved because with PlasACRYL T20, processes such as homogenisation, heating and cooling down can be skipped and the number of weighing steps can be decreased.

Depending on the formulation, the duration of the coating process can be reduced considerably. In addition, this additive eliminates the tackiness of acrylic materials and prevents the clogging of lines and nozzles. Furthermore, the spray suspension does not settle or separate, so constant stirring is not required.

These factors lead to lower production costs as a result of lower energy consumption and fewer process steps and batch failures.

The product is compatible with all EUDRAGIT grades and is most frequently used with EUDRAGIT L 30 D-55 for enteric coatings and with EUDRAGIT FS 30 D for colonic delivery. Whether you want to coat tablets, capsules or particles, the easy-to-use PlasACRYL T20 can become your preferred component in combination with EUDRAGIT.

Thanks to the cooperation between Emerson Resources, the manufacturer of PlasACRYL T20, and Evonik, the exclusive worldwide distributor, pharmaceutical formulators now have easier access to this innovative coating system. For more information and samples, please contact the Evonik Pharma Polymers representatives in your region.

Pharma Polymers, a business line of Evonik Industries, holds a leading market position for functional coating polymers. The variety of EUDRAGIT acrylic drug delivery polymers provides full flexibility for enteric, sustainedrelease and protective applications.

Evonik also provides a versatile range of services that extend far beyond the actual product. The company is a reliable partner for the pharmaceutical industry that supports its customers at every stage of drug development: The service portfolio includes feasibility studies, formulation development, clinical supply manufacturing, scale-up and technology transfer to the commercial production site.

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Tel: +49 615 118 4019
URL: www.eudragit.com

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